Welcome to Open Door Animal Sanctuary!  

 Open Door Animal Sanctuary, founded in 1975, is the largest no-kill sanctuary in the greater St. Louis area and State of Missouri.  Open Door’s Mission is to provide homeless cats and dogs with the highest quality of life and a second chance to find a forever family.  

We serve the community by taking in stray, abused, neglected and otherwise unwanted cats and dogs and placing them up for adoption. Each day we provide shelter, food, medical care and LOVE to over 400 animals.

Every animal that comes to us has a home and a second chance at life. If you are looking to adopt a dog or cat, we have the most animals to choose from in the area! Our adoption fee ($150 for puppies, dogs, and kittens and $75 for adult cats) includes spay/neuter, a microchip, the first two sets of shots and parasite preventative. Dogs are tested for heartworm and cats are tested for FIV/FeLeuk prior to adoption.  Come check out all our great dogs and cats!